Wiskostatin is a cell-permeable N-alkylated carbazole derivative that selectively blocks actin filament assembly. The compound acts as a selective, reversible inhibitor of N-WASP (neural Wiskott Aldrich syndrome protein), a signal integrating protein. Wiskostatin also binds to N-WASP, stabilize the autoinhibited conformation and prevent the activation of Arp2/3 (actin-related protein 2/3) complex. 神经Wiskott-Aldrich综合征蛋白（N-WASP）活性抑制剂 Wiskostatin is a cell-permeable N-alkylated carbazole derivative that selectively blocks actin filament assembly. The compound acts as a selective, reversible inhibitor of N-WASP (neural Wiskott Aldrich syndrome protein), a signal integrating protein. Wiskostatin also binds to N-WASP, stabilize the autoinhibited conformation and prevent the activation of Arp2/3 (actin-related protein 2/3) complex. Wiskostatin is a selective inhibitor of actin filament assembly
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Wiskostatin
Dangerous GoodsCAS number：253449-04-6 molecular formula：C17H18Br2N2O
overview
compound introduction
Specs
| Chinese alias | 1-(3,6-二溴卡巴唑-9-基)-3-(二甲氨基)丙-2-醇 | ||
| English alias | AS-75867 | J-503093 | KBioGR_000620 | 3,6-Dibromo-alpha-[(dimethylamino)methyl ]-9H-cabazole-9-ethanol | CBDivE_008357 | Oprea1_105682 | C17H18Br2N2O | MFCD00218393 | Oprea1_198540 | Wiskostatin | KBio3_001099 | NCGC00163493-02 | HY-12534 | NCGC00179231-0 | ||
| CAS number | 253449-04-6 | molecular formula | C17H18Br2N2O |
| molecular weight | 426.15 g/mol | Exact mass | ≥98%(HPLC) |
| PSA | 28.400 Ų | logp | 4.100 |
numbering system
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physicochemical properties
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Safety information
pictogram：
GHS06
Signal word：
Danger
Hazard Statement：
H301: 吞咽会中毒 H413: 可能对水生生物造成长期的有害影响
Statement of Preventive Measures：
P273: 避免释放到环境中。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P330: 漱口 P301+P316: 如果吞咽：立即寻求紧急医疗救助。
WGK Germany：
3
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MSDS
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