JMS-17-2

Dangerous Goods

CAS number：1380392-05-1 molecular formula：C25H26ClN3O

overview

Specs

numbering system

physicochemical properties

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Production methods and uses

MSDS

overview

compound introduction

Information JMS-17-2 JMS-17-2 is a potent and selective small-molecule antagonist of CX3C chemokine receptor 1 (CX3CR1/GPR13) with IC50 of 0.32 nM. JMS-17-2 is used in the research of metastatic disease in breast cancer patients. Targets GPR13 (Cell-free assay) 0.32 nM

Specs

Chinese alias	-
English alias	5-(3-(4-(4-chlorophenyl)piperidin-1-yl)propyl)pyrrolo[1,2-a]quinoxalin-4(5H)-one
CAS number	1380392-05-1	molecular formula	C25H26ClN3O
molecular weight	419.95 g/mol	Exact mass	-
PSA	28.500 Å²	logp	5.224

numbering system

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physicochemical properties

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Safety information

pictogram：

GHS07

Signal word：

Warning

Hazard Statement：

H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激

Statement of Preventive Measures：

P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P301+P312: 如误吞咽：如感觉不适，呼叫急救中心/医生。