compound introduction
H-151 是一种有效，选择性和共价的 STING 拮抗剂，在体外和体内均具有显着的抑制活性。H-151 减少 TBK1 磷酸化并抑制 STING 棕榈酰化。H-151 可用于自身炎症性疾病的研究。
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H 151
Dangerous GoodsCAS number：941987-60-6 molecular formula：C17H17N3O
overview
Specs
| Chinese alias | 1-(4-乙基苯基)-3-(1H-吲哚-3-基)脲 | ||
| English alias | 1-(4-ethylphenyl)-3-(1H-indol-3-yl)urea | 3-(4-ethylphenyl)-1-(1H-indol-3-yl)urea | N-(4-ethylphenyl)-N'-1H-indol-3-yl-urea | H-151 | ||
| CAS number | 941987-60-6 | molecular formula | C17H17N3O |
| molecular weight | 279.34 g/mol | Exact mass | - |
| PSA | 56.900 Ų | logp | 3.400 |
numbering system
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physicochemical properties
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Safety information
pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。
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MSDS
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