HC-030031是TRPA1通道阻断剂,能拮抗AITC和福尔马林诱发的钙流,IC50分别为6.2 μM和5.3 μM。 A potent and selective TRPA1 inhibitor HC-030031 is a selective TRPA1 channel blocker that antagonizes AITC- and formalin-evoked calcium influx with IC50 of 6.2 μM and 5.3 μM respectively. A potent and selective TRPA1 inhibitor
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HC-030031
Dangerous GoodsCAS number:349085-38-7 molecular formula:C18H21N5O3
overview
compound introduction
Specs
| Chinese alias | 1,2,3,6-四氢-1,3-二甲基-N- [4-(1-甲基乙基)苯基]-2,6-二氧代-7H-嘌呤-7-乙酰胺 | 2-(1,3-二甲基-2,6-二氧代-1,2,3,6-四氢-7H-嘌呤-7-基)-N-(4-异丙基苯基)乙酰胺 | ||
| English alias | HC 030031 | HC030031 | FT-0669107 | TOSLAB 829227 | BDBM50318463 | NCGC00378740-04 | Oprea1_280240 | 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropurin-7-yl)-N-(4-isopropylphenyl)acetamide | AC-32672 | 2-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin- | ||
| CAS number | 349085-38-7 | molecular formula | C18H21N5O3 |
| molecular weight | 355.39 g/mol | Exact mass | - |
| PSA | 87.500 Ų | logp | 1.700 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram:
GHS06
Signal word:
Danger
Hazard Statement:
H301: 吞咽会中毒
Statement of Preventive Measures:
P321: 特殊处理(请参阅此标签上的...)。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P330: 漱口 P301+P316: 如果吞咽:立即寻求紧急医疗救助。
WGK Germany:
3
Personal protective equipment:
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Production methods and uses
No production method and use information yet
Related
upstream information
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downstream information
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MSDS
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