Fmoc-L-Tyr(2,6-Cl2-Bzl)-OH是Fmoc保护的酪氨酸衍生物,可能对蛋白质组学研究和固相肽合成技术有用。酪氨酸是一种非常重要的氨基酸-少数被磷酸化以改变肽的物理性质的氨基酸之一,并且是形成碘化甲状腺激素的前体。通常用诸如吡啶之类的碱除去Fmoc基团-这是酸性labile Boc基团的正交脱保护策略。 Fmoc-L-Tyr(2,6-Cl2-Bzl)-OH is an Fmoc protected tyrosine derivative that is potentially useful for proteomics studies and solid phase peptide synthesis techniques. Tyrosine is a very important amino acid - one of the few amino acids which is phosphorylated to vary the physical properties of the peptides, and is a precursor for the formation of iodinated thyroid hormones. The Fmoc group is typically removed with a base such as pyridine - an orthogonal de-protection strategy to the acid labilie Boc group.
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Fmoc-L-Tyr(2,6-Cl2-Bzl)-OH
Dangerous GoodsCAS number:112402-12-7 molecular formula:C31H25Cl2NO5
overview
compound introduction
Specs
| Chinese alias | O-[(2,6-二氯苯基)甲基]-N-[(9H-芴-9-基甲氧基)羰基]-L-酪氨酸 | ||
| English alias | AKOS027340197 | DTXSID30634731 | BS-25982 | Fmoc-L-Tyr(2,6-Cl2-Bzl)-OH | J-002766 | MFCD00065685 | (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-((2,6-dichlorobenzyl)oxy)phenyl)propanoic acid | N-alpha-(9-Fluorenylmethyloxycarbonyl)-O-(2,6-dichlo | ||
| CAS number | 112402-12-7 | molecular formula | C31H25Cl2NO5 |
| molecular weight | 562.44 g/mol | Exact mass | ≥96% |
| PSA | 84.900 Ų | logp | 7.400 |
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physicochemical properties
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Safety information
pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H319: 引起严重眼睛刺激 H412: 对水生生物有害并具有长期持续影响 H302: 吞食有害
Statement of Preventive Measures:
P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
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