Description A novel derivative for the introduction of monomethyl-lysine during Fmoc SPPS [1, 2]. Coupling can be carried out using any standard activation method. Removal of the Boc protecting group occurs during the course of the TFA-mediated cleavage reaction. Ref [3] contains methods and protocols for the synthesis of arrays of histone-related peptides containing methylated arginine and lysine-residues.The product number for this product was previously 04-12-1263..
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Fmoc-Lys(Me,Boc)-OH
Dangerous GoodsCAS number:951695-85-5 molecular formula:C27H34N2O6
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | N~6~-(tert-Butoxycarbonyl)-N~2~-{[(9H-fluoren-9-yl)methoxy]carbonyl}-N~6~-methyl-L-lysine | Fmoc-Lys(Boc,Me)-OH | MFCD01861332 | A14947 | DTXSID70657020 | Fmoc-Lys(Me,Boc)-OH, AldrichCPR | N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-epsilon-t-butyl-oxycarbon | ||
| CAS number | 951695-85-5 | molecular formula | C27H34N2O6 |
| molecular weight | 482.57 g/mol | Exact mass | ≥99% |
| PSA | 105.000 Ų | logp | 4.600 |
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Safety information
pictogram:
GHS09
Signal word:
Warning
Hazard Statement:
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H302: 吞食有害 H400: 对水生生物有剧毒 H410: 对水生生物有剧毒并具有长期持续影响
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。 P273: 避免释放到环境中。 P501: 将内容物/容器处理到。。。 P391: 收集溢出物
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