Description Neutral Protease AF is derived from C. histolyticum using a production process completely free of any animal based components. Thus, any risk of transmission of potential animal-derived pathogens is excluded. This purified metalloprotease is suitable for the dissociation of tissue in clinical applications. For especially gentle cell isolation it is recommended to use Neutral Protease AF in combination with highly purified Collagenase AF-1 Specifications Plant-based fermentation process. Contains chromatographically purified neutral protease. Vial contains not less than 100 DMC U of neutral protease. Neutral protease activity (DMC) ≥ 0.50 U/mg. Endotoxin: ≤ 100 EU/mg (Ph. Eur.) Largely free of collagenolytic activity. Microbiological examination: Total aerobic microbial count (TAMC), total combined yeast/moulds count (TYMC), absence of Clostridia Endproduct is 0.22 µm filtered. References and Definitions Unit definition:Neutral Protease: 1 DMC Unit catalyzes the cleavage of 1 µmol peptide bond from dimethylcasein per minute at 25 °C, pH 7.0, expressed in terms of newly formed terminal amino groups, determined with TNBS (1). Endotoxin: Ph. Eur. [1 Endotoxin Unit is equal to 1 International Unit of a WHO approved reference standard endotoxin (RSE)]. References 1. Lin, Y.-C. et al. (1969) J. Biol. Chem. 244, 789-93 Description Neutral Protease AF is derived from C. histolyticum using a production process completely free of any animal based components. Thus, any risk of transmission of potential animal-derived pathogens is excluded. This purified metalloprotease is suitable for the dissociation of tissue in clinical applications. For especially gentle cell isolation it is recommended to use Neutral Protease AF in combination with highly purified Collagenase AF-1 Specifications Plant-based fermentation process. Contains chromatographically purified neutral protease. Vial contains not less than 100 DMC U of neutral protease. Neutral protease activity (DMC) ≥ 0.50 U/mg. Endotoxin: ≤ 100 EU/mg (Ph. Eur.) Largely free of collagenolytic activity. Microbiological examination: Total aerobic microbial count (TAMC), total combined yeast/moulds count (TYMC), absence of Clostridia Endproduct is 0.22 µm filtered. References and Definitions Unit definition:Neutral Protease: 1 DMC Unit catalyzes the cleavage of 1 µmol peptide bond from dimethylcasein per minute at 25 °C, pH 7.0, expressed in terms of newly formed terminal amino groups, determined with TNBS (1). Endotoxin: Ph. Eur. [1 Endotoxin Unit is equal to 1 International Unit of a WHO approved reference standard endotoxin (RSE)]. References 1. Lin, Y.-C. et al. (1969) J. Biol. Chem. 244, 789-93
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中性蛋白酶 AF 来源于溶组织梭菌
Dangerous GoodsCAS number：unknown molecular formula：
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | Neutral Protease | ||
| CAS number | unknown | molecular formula | |
| molecular weight | - | Exact mass | - |
| PSA | - | logp | - |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram：
GHS08 , GHS07
Signal word：
Danger
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H334: 吸入可能引起过敏或哮喘病症状或呼吸困难
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P342+P311: 如有呼吸系统病症：呼叫急救中心/医生。
WGK Germany：
1
Personal protective equipment：
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
RTECS：
UK9540000
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
No downstream information yet
MSDS
Found 0 shareMSDS
