BAY 11-7082是一种NF-κB抑制剂,抑制TNFα诱导的IκBα磷酸化,IC50为10 μM。同时对泛素化系统的组分也有抑制作用。An anti-inflammatory agent and NFκB inhibitor BAY 11-7082 is a NF-κB inhibitor, inhibits TNFα-induced IκBα phosphorylation with IC50 of 10 μM. Also inhibiting components of the ubiquitin system. An anti-inflammatory agent and NFκB inhibitor
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BAY 11-7082
Dangerous GoodsCAS number:19542-67-7 molecular formula:C10H9NO2S
overview
compound introduction
Specs
| Chinese alias | (E)-3-甲苯磺酰基丙烯腈 | (E)-3-(4-甲苯磺酰基)-2-丙烯腈 | (E)-3-(对甲苯磺酰基)丙烯 | ||
| English alias | 7-Chloro-1-cyclopropylmethyl-5-phenyl-1H-1,4-benzodiazepin-2(3H)-one | CHEBI:92270 | Cyanovinyl)-p-tolylsulfone, beta-( | J-501956 | UNII-4Y5G2A4F6O | Curator_000002 | HMS3678M15 | (2E)-3-(4-methylbenzenesulfonyl)prop-2-enenitrile | NCGC00025272-03 | NCGC | ||
| CAS number | 19542-67-7 | molecular formula | C10H9NO2S |
| molecular weight | 207.25 g/mol | Exact mass | - |
| PSA | 66.300 Ų | logp | 1.400 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H302: 吞食有害
Statement of Preventive Measures:
P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染:用水充分清洗。 P321: 特殊处理(请参阅此标签上的...)。 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P362+P364: 脱掉沾污的衣服,清洗后方可重新使用。 P330: 漱口 P264+P265: 处理后彻底
WGK Germany:
3
Personal protective equipment:
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
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MSDS
Found 0 shareMSDS





