Fasentin 是有效的葡萄糖摄取抑制剂,可抑制 GLUT-1/GLUT-4 转运蛋白。Fasentin 优先抑制 GLUT4 (IC50=68 μM)。Fasentin 是死亡受体刺激 (FAS) 敏化剂,可敏化细胞对 FAS 诱导的细胞死亡。Fasentin 也是诱导肿瘤坏死因子 (TNF) 凋亡配体的敏化剂。Fasentin 阻断癌细胞系中的葡萄糖摄取,并具有抗血管生成活性。
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Fasentin
Dangerous GoodsCAS number:392721-37-8 molecular formula:C11H9ClF3NO2
overview
compound introduction
Specs
| Chinese alias | N-(4-氯-3-(三氟甲基)苯基)-3-氧代丁酰胺 | ||
| English alias | SCHEMBL2350751 | STL582160 | BF167835 | GNYIJZMBLZXJEJ-UHFFFAOYSA-N | SR-01000227427-1 | Fasentin | SMSF0013818 | Z57515202 | SR-01000227427 | MFCD01001285 | NCGC00485097-01 | A858091 | HY-101849 | DTXSID60358175 | BS-51102 | CB12214 | AC-36403 | Fasentin | ||
| CAS number | 392721-37-8 | molecular formula | C11H9ClF3NO2 |
| molecular weight | 279.64 g/mol | Exact mass | ≥98%(HPLC) |
| PSA | 46.200 Ų | logp | 3.700 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H302: 吞食有害
Statement of Preventive Measures:
P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P330: 漱口 P301+P317: 如果被吞咽:请寻求医疗帮助。
Production methods and uses
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upstream information
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downstream information
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MSDS
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