BRD9757 是一种有效的、无帽的、选择性的 HDAC6 抑制剂,IC50 为 30 nM。与 I 类(>20 倍)和 II 类(>400 倍)HDAC 相比,BRD9757 对 HDAC6 表现出出色的选择性。 BRD9757 is a potent, capless and selective HDAC6 inhibitor with an IC50 of 30 nM. BRD9757 shows excellent selectivity toward HDAC6 versus the class I (>20-fold) and class II (>400-fold) HDACs.
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BRD 9757
Dangerous GoodsCAS number:1423058-85-8 molecular formula:C6H9NO2
overview
compound introduction
Specs
| Chinese alias | N-羟基-1-环戊烯-1-羧酰胺 | ||
| English alias | AKOS040746645 | N-Hydroxy-1-cyclopentene-1-carboxamide | N-hydroxycyclopentene-1-carboxamide | cyclopentenylhydroxamate | FBJ | BDBM50429525 | Q27215669 | HY-117554 | YGC05885 | 1423058-85-8 | CHEBI:125319 | SCHEMBL6880360 | cyclopentenyl hydroxamic acid | ||
| CAS number | 1423058-85-8 | molecular formula | C6H9NO2 |
| molecular weight | 127.14 g/mol | Exact mass | ≥98%(HPLC) |
| PSA | 49.300 Ų | logp | 0.400 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H319: 引起严重眼睛刺激 H412: 对水生生物有害并具有长期持续影响
Statement of Preventive Measures:
P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。 P273: 避免释放到环境中。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P501: 将内容物/容器处理到。。。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P337+P317: 如果眼睛刺激持续:寻求医疗帮助。
WGK Germany:
3
Production methods and uses
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MSDS
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