ARP101 是一种有效的选择性抑制剂基质金属蛋白酶-2 (MMP-2)。ARP101 在癌细胞中诱导自噬相关的细胞死亡。ARP101可有效诱导自噬体形成和LC3I转化为LC3II。 ARP101 is a potent and selective inhibitor matrix metalloproteinase-2 (MMP-2). ARP101 induces autophagy-associated cell death in cancer cells. ARP101 is effective in inducing the formation of autophagosome and conversion of LC3I into LC3II.
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ARP 101
Dangerous GoodsCAS number:849773-63-3 molecular formula:C20H26N2O5S
overview
compound introduction
Specs
| Chinese alias | (R)-N-羟基-2-(N-异丙氧基联苯-4-基磺酰胺基)-3-甲基丁酰胺 | ||
| English alias | CHEBI:93296 | HMS3269F17 | (2R)-2-[([1,1'-Biphenyl]-4-ylsulfonyl)(1-methylethoxy)amino]-N-hydroxy-3-methyl-butanamide | (R)-N-HYDROXY-2-(N-ISOPROPOXYBIPHENYL-4-YLSULFONAMIDO)-3-METHYLBUTANAMIDE | Q27165008 | SCHEMBL13738485 | (R)-2-[(Biphenyl-4-sulfonyl)- | ||
| CAS number | 849773-63-3 | molecular formula | C20H26N2O5S |
| molecular weight | 406.5 g/mol | Exact mass | ≥96% |
| PSA | 104.000 Ų | logp | 3.800 |
numbering system
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physicochemical properties
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Safety information
pictogram:
GHS06
Signal word:
Danger
Hazard Statement:
H301: 吞咽会中毒
Statement of Preventive Measures:
P321: 特殊处理(请参阅此标签上的...)。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P330: 漱口 P301+P316: 如果吞咽:立即寻求紧急医疗救助。
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