Chlorisondamine (diiodide) 是一种有效的尼古丁乙酰胆碱受体 (nAChR) 拮抗剂和神经节阻断剂。Chlorisondamine 能有效、持久地拮抗尼古丁的一些中枢作用，并具有药理学选择性。 Chlorisondamine (diiodide) is a potent nicotinic acetylcholine receptor (nAChR) antagonist and a ganglion blocker. Chlorisondamine antagonizes some of nicotine's central actions in a potent, long-lasting and pharmacologically selective way. Product Application: Chlorisondamine diiodide has been used: as a nicotinic receptor antagonist to test its effect on trinitrobenzene sulfonic acid (TNBS)-induced colitis as an irreversible nicotinic acetylcholine(nAChR) blocker to pre-treat brain samples to test its effect on cytochrome P450 2B (CYP2B) induction as a ganglionic blocker to test its effect on regulating corticosterone levels in rat with chronic stress.
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Chlorisondamine diiodide
Dangerous GoodsCAS number：96750-66-2 molecular formula：C14H20Cl4I2N2
overview
compound introduction
Specs
| Chinese alias | 4,5,6,7-四氯-1,3-二氢-2-甲基-2-[2-三甲基铵)乙基] -2H-二碘异吲哚鎓 | 氯硝西泮二碘化物 | ||
| English alias | Chlorisondamine diiodide, >=98% (HPLC), white solid | trimethyl-[2-(4,5,6,7-tetrachloro-2-methyl-1,3-dihydroisoindol-2-ium-2-yl)ethyl]azanium;diiodide | 4,5,6,7-tetrachloro-2-methyl-2-(2-(trimethylammonio)ethyl)isoindolinium iodide | HMS3678J05 | 4,5,6,7- | ||
| CAS number | 96750-66-2 | molecular formula | C14H20Cl4I2N2 |
| molecular weight | 611.95 g/mol | Exact mass | ≥99%(HPLC) |
| PSA | 0.000 Ų | logp | - |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram：
GHS09 , GHS07
Signal word：
Warning
Hazard Statement：
H302: 吞食有害 H400: 对水生生物有剧毒
Statement of Preventive Measures：
P273: 避免释放到环境中。 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P391: 收集溢出物 P330: 漱口 P301+P317: 如果被吞咽：请寻求医疗帮助。
WGK Germany：
2
Personal protective equipment：
dust mask type N95 (US)， Eyeshields， Gloves
Production methods and uses
No production method and use information yet
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upstream information
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downstream information
No downstream information yet
MSDS
Found 0 shareMSDS
