CAS number：117857-45-1 molecular formula：C10H6Cl3N3
盐酸洛雷克唑是亚型选择性的GABA | A |受体激动剂。含有β2或β3亚基的受体的正变构调节剂。在新的调节位点还充当负调节剂，从而增强GABA | A |受体的敏感性。抑制同型ρ1GABA | C |受体。 Loreclezole hydrochloride is a subtype-selective GABA|A|receptor agonist. Positive allosteric modulator of β2 or β3-subunit containing receptors. Also acts as a negative modulator at a novel regulatory site, enhancing GABA|A|receptor sensitization. Inhibits homomeric ρ1 GABA|C|receptors.
| Chinese alias | 氯瑞唑 | 洛雷唑 | ||
| English alias | HY-105272 | BS-14505 | Loreclezole [USAN:INN:BAN] | 6DJ32STZ5W | DTXSID6048252 | LORECLEZOLE [USAN] | R 72063 | Loreclezol [INN-Spanish] | Loreclezole | GTPL5466 | LORECLEZOLE [INN] | (Z)-1-(.beta.,2,4-Trichlorostyryl)-1H-1,2,4-triazole | ||
| CAS number | 117857-45-1 | molecular formula | C10H6Cl3N3 |
| molecular weight | 274.53 g/mol | Exact mass | - |
| PSA | 30.700 Ų | logp | 3.800 |
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