Information VBIT-4 VBIT-4 is a voltage-dependent anion channel (VDAC) oligomerization inhibitor that decreases mitochondrial DNA (mtDNA) release, type I interferon (IFN) signaling, neutrophil extracellular traps, and disease severity in a mouse model of systemic lupus erythematosus. Targets VDAC ; mtDNA ; IFN
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VBIT-4
Dangerous GoodsCAS number:2086257-77-2 molecular formula:C21H23ClF3N3O3
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | N-(4-chlorophenyl)-4-hydroxy-3-[4-[4-(trifluoromethoxy)phenyl]piperazin-1-yl]butanamide | SCHEMBL18641899 | Z2074895470 | EX-A5330 | N-(4-chlorophenyl)-4-hydroxy-3-{4-[4-(trifluoromethoxy)phenyl]piperazin-1-yl}butanamide | QYSQXVAEFPWMEM-UHFFFAOYSA-N | EN | ||
| CAS number | 2086257-77-2 | molecular formula | C21H23ClF3N3O3 |
| molecular weight | 457.87 g/mol | Exact mass | 10mM in DMSO |
| PSA | 65.000 Ų | logp | 3.900 |
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physicochemical properties
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Safety information
pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染:用水充分清洗。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P312: 打电话给毒物中心或医生。。。如果你觉得不舒服 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P362: 脱下污染的衣服并洗净
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