CAS number：354812-17-2 molecular formula：C9H8N2OS2
SC-514是一种口服有效的，ATP竞争性的IKK-2抑制剂，IC50为3-12 μM，抑制NF-κB依赖性的基因表达，不抑制其他IKK异构体或其他丝-苏氨酸和酪氨酸激酶。A selective and reversible inhibitor of IKKβ (IKK-2) SC-514 is an orally active, ATP-competitive IKK-2 inhibitor with IC50 of 3-12 μM, blocks NF-κB-dependent gene expression, does not inhibit other IKK isoforms or other serine-threonine and tyrosine kinases. A selective and reversible inhibitor of IKKβ (IKK-2)
| Chinese alias | - | ||
| English alias | 4-amino-2,3'-bithiophene-5-carboxamide | BCP21098 | 4-Amino-[2',3'-bithiophene]-5-carboxamide | 4-Amino-[2,3'-bithiophene]-5-carboxamide | 4-Amino[2,3'-bithiophene]-5-carboxamide | FT-0674534 | NCGC00163392-01 | s4907 | 5-(Thien-3-yl)-3-aminothiophene-2-c | ||
| CAS number | 354812-17-2 | molecular formula | C9H8N2OS2 |
| molecular weight | 224.3 g/mol | Exact mass | ≥98% |
| PSA | 126.000 Ų | logp | 2.000 |
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