CAS number：940310-85-0 molecular formula：C26H20F3N7O
NVP-BHG712是EphB4抑制剂，ED50为25 nM，对c-Raf，c-Src和c-Abl的IC50分别为0.395 μM，1.266 μM和1.667 μM。 NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR and EphB4 inhibition; also shows activity against c-Raf, c-Src and c-Abl with IC50 of 0.395 μM, 1.266 μM and 1.667 μM, respectively.
| Chinese alias | 4-甲基-3-[[1-甲基-6-(3-吡啶基)-1H-吡唑并[3,4-d]嘧啶-4-基]氨基]-N-[3-(三氟甲基)苯基]苯甲酰胺 | ||
| English alias | 4-Methyl-3-(1-methyl-6-pyridin-3-yl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamino)-N-(3-trifluoromethyl-phenyl)-benzamide | Benzamide, 4-methyl-3-((1-methyl-6-(3-pyridinyl)-1H-pyrazolo(3,4-d)pyrimidin-4-yl)amino)-N-(3-(trifluoromethyl)phenyl)- | CHEBI:91447 | BCP | ||
| CAS number | 940310-85-0 | molecular formula | C26H20F3N7O |
| molecular weight | 503.48 g/mol | Exact mass | ≥98% |
| PSA | 97.600 Ų | logp | 4.700 |
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