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LFM-A13

Dangerous Goods

CAS number：244240-24-2    molecular formula：C11H8Br2N2O2

overview
Specs
numbering system
physicochemical properties
Safety information
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overview

compound introduction

LFM-A13是一种特异性布鲁顿氏酪氨酸激酶(BTK)抑制剂，IC50为2.5 μM,选择性比其他蛋白激酶，包括JAK1，JAK2，HCK，EGFR，和 IRK高100多倍。 LFM-A13 是一种有效的 BTK，JAK2，PLK 抑制剂，可抑制 BTK，Plx1 和 PLK3 的活性，IC50 分别为 2.5 μM，10 μM 和 61 μM。 Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Specs

Chinese alias2-氰基-N-(2,5-二溴苯基)-3-羟基丁-2-烯酰胺
English aliasCCG-100654 | NCGC00025100-02 | Lopac0_000650 | a-Cyano-b-hydroxy-b-methyl-N-(2,5-dibromophenyl)propenamide | BDBM50552060 | DTXSID101017390 | K00067 | L 8789 | alpha-Cyano-beta-hydroxy-beta-methyl-N-(2,5-dibromophenyl)propenamide | SR-01000075965-3 | (Z)-
CAS number244240-24-2molecular formulaC11H8Br2N2O2
molecular weight360 g/molExact mass-
PSA73.100 Ųlogp3.800

numbering system

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physicochemical properties

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Safety information

pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H302+H312+H332: 吞咽，皮肤接触或吸入有害。
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。

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