CAS number：213743-31-8 molecular formula：C23H22N4O
Lck抑制剂是一种细胞可透过的吡咯并嘧啶化合物，可作为Lck的有效，选择性和ATP竞争性抑制剂（IC | 50 |在5μM时ATP = Lck Inhibitor is a cell-permeable pyrrolopyrimidine compound that acts as a potent, selective, and ATP-competitive inhibitor of Lck (IC|50|at 5 μM ATP = 33 μM, > 50 μM and > 50 μM for EGFR, PKC, CDC2/B and ZAP-70, respectively). Also shown to potently block T-cell receptor-stimulated IL-2 production in vitro (IC50
| Chinese alias | - | ||
| English alias | 4-Amino-7-cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidine | N16945 | HMS3261I22 | RK 24466 | CCG-204542 | NCGC00015280-05 | RK24466 | RK-24466 | 7-Cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine, >=98% (HPLC) | B43 | NCGC0 | ||
| CAS number | 213743-31-8 | molecular formula | C23H22N4O |
| molecular weight | 370.45 g/mol | Exact mass | - |
| PSA | 66.000 Ų | logp | 4.600 |
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