CAS number：1202759-32-7 molecular formula：C26H22FN7O3
Information CNX-774 CNX-774 is an irreversible, orally active, and highly selective BTK inhibitor with IC50 of Targets BTK In vitro In cellular assays, CNX-774 demonstrates potent inhibitory activity towards BTK with IC50 of 1-10 nM by targeting Cys-481 residue within the ATP binding site of the enzyme.
| Chinese alias | - | ||
| English alias | 4-(4-((4-((3-acrylamidophenyl)amino)-5-fluoropyrimidin-2-yl)amino)phenoxy)-N-methylpicolinamide | ||
| CAS number | 1202759-32-7 | molecular formula | C26H22FN7O3 |
| molecular weight | 499.5 g/mol | Exact mass | - |
| PSA | 130.000 Ų | logp | 3.900 |
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