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8-Hydroxyquinoline-5-carboxylic Acid

Dangerous Goods

CAS number：5852-78-8    molecular formula：C10H7NO3

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physicochemical properties
Safety information
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overview

compound introduction

用途 消除潜伏病毒的病毒潜伏期，以使病毒感染对抗病毒治疗敏感。 在组蛋白赖氨酸脱甲基酶4A（KDM4A）抑制中，作为减少缺氧诱导因子信号传导的独特策略。 恢复癌基因诱导的野生型小鼠胚胎成纤维细胞衰老。 产品介绍 IOX1，是 2OG 氧合酶 (2OG oxygenases) 的有效广谱抑制剂，包括 JmjC 去甲基酶。IOX1 抑制 KDM4C，KDM4E，KDM2A，KDM3A 和 KDM6B 的 IC50 值分别为 0.6 μM，2.3 μM，1.8 μM，0.1 μM 和 1.4 μM。IOX1 抑制 ALKBH5。

Specs

Chinese alias-
English aliasIOX1 | SCHEMBL6068195 | AKOS028109012 | Z1255461048 | 5-carboxy-8HQ | AMY6925 | PS-11320 | IOX1 compound | DTXSID20207236 | GTPL8230 | HY-12304 | 4bio | 8-Hydroxyquinoline-5-CarboxylicAcid | SB12855 | 5-Carboxy-8-hydroxyquinoline | IOX1, >=97% (HPLC) | SM
CAS number5852-78-8molecular formulaC10H7NO3
molecular weight189.17 g/molExact mass-
PSA70.400 Ųlogp1.800

numbering system

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physicochemical properties

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Safety information

pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H302: 吞食有害
Statement of Preventive Measures：
P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P330: 漱口 P301+P317: 如果被吞咽：请寻求医疗帮助。
WGK Germany：
3

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