EX 527 (Selisistat)是一种有效的,选择性的SIRT1抑制剂,IC50为38 nM,比作用于SIRT2和SIRT3选择性高200倍以上。A selective inhibitor of SIRT1 over SIRT2 and SIRT3 EX 527 is a potent and selective SIRT1 inhibitor with IC50 of 38 nM, exhibits >200-fold selectivity against SIRT2 and SIRT3. A selective inhibitor of SIRT1 over SIRT2 and SIRT3
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EX 527 (Selisistat)
Dangerous GoodsCAS number:49843-98-3 molecular formula:C13H13ClN2O
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | EX-527 (SELISISTAT) | SEN0014196 | SEN-0014196 | AB88646 | 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide | FT-0698480 | SELISISTAT [WHO-DD] | SCHEMBL1275557 | 1H-Carbazole-1-carboxamide, 6-chloro-2,3,4,9-tetrahydro- | EX 527 | HMS3426E09 | 6-Chlo | ||
| CAS number | 49843-98-3 | molecular formula | C13H13ClN2O |
| molecular weight | 248.71 g/mol | Exact mass | - |
| PSA | 58.900 Ų | logp | 2.500 |
numbering system
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physicochemical properties
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Safety information
pictogram:
GHS06 , GHS07
Signal word:
Danger
Hazard Statement:
H319: 引起严重眼睛刺激 H301: 吞咽会中毒
Statement of Preventive Measures:
P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P321: 特殊处理(请参阅此标签上的...)。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P330: 漱口 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P301+P316: 如果吞咽:立即寻求紧急医疗救助。 P
WGK Germany:
3
Production methods and uses
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downstream information
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MSDS
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