CAS number：1340593-59-0 molecular formula：C23H16F7N5O2
Oteseconazole (VT-1161) 是一种有效的抗真菌剂。Oteseconazole 有效结合并抑制白色念珠菌 (Candida albicans) 中细胞色素 P45051 (CYP51) 活性 (Kd ≤39 nM, MIC=0.002 μg/mL)，但对人 CYP51 无明显作用。Oteseconazole 还可用于皮肤癣菌的研究 Oteseconazole (VT-1161) is an effective antifungal agent. Oteseconazole effectively binds to and inhibits cytochrome P45051 (CYP51) activity in Candida albicans (Kd ≤39 nM, MIC=0.002 μg/mL), but has no significant effect on human CYP51. Oteseconazole can also be used in the study of dermatophyton
| Chinese alias | 奥替康唑 | ||
| English alias | CHEBI:188153 | Oteseconazole | 1340593-59-0 | 2-Pyridineethanol, alpha-(2,4-difluorophenyl)-beta,beta-difluoro-alpha-(1H-tetrazol-1-ylmethyl)-5-[4-(2,2,2-trifluoroethoxy)phenyl]-, (alphaR)- | D87154 | VIVJOA | CAS-14639-25-9 | IDUYJRXRDSPPRC-NRFANRHFSA-N | ||
| CAS number | 1340593-59-0 | molecular formula | C23H16F7N5O2 |
| molecular weight | 527.39 g/mol | Exact mass | ≥99% |
| PSA | 86.000 Ų | logp | 4.2 |
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