(R)-(-)-Gossypol acetic acid

Dangerous Goods

CAS number：866541-93-7 molecular formula：C30H30O8·xC2H4O2

overview

Specs

numbering system

physicochemical properties

Safety information

Production methods and uses

MSDS

overview

compound introduction

(R)-(-)-Gossypol acetic acid (AT-101 (acetic acid)) 是天然产物 Gossypol 的左旋异构体。AT-101 结合到 Bcl-2，Mcl-1 和 Bcl-xL 蛋白，Ki 值分别为 260±30 nM，170±10 nM 和 480±40 nM。 Product Describtion: (R)-(-)-Gossypol acetic acid (AT-101 (acetic acid)) is the levorotatory isomer of a natural product Gossypol. AT-101 is determined to bind to Bcl-2, Mcl-1 and Bcl-xL proteins with Kis of 260±30 nM, 170±10 nM, and 480±40 nM, respectively.

Specs

Chinese alias	(R)-棉子酚乙酸盐
English alias	U9GNI6VT5N \| AC-34098 \| Acetic acid--1,1',6,6',7,7'-hexahydroxy-3,3'-dimethyl-5,5'-di(propan-2-yl)[2,2'-binaphthalene]-8,8'-dicarbaldehyde (1/1) \| AT 101 acetic acid \| A13578 \| Gossypol acetic acid clathrate \| gossypol-Acetic acid \| J-005228 \| 1189561-66-
CAS number	866541-93-7	molecular formula	C30H30O8·xC2H4O2
molecular weight	518.55（free） g/mol	Exact mass	分析标准品
PSA	193.000 Å²	logp	-

numbering system

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physicochemical properties

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Safety information

pictogram：

GHS08 , GHS07

Signal word：

Warning

Hazard Statement：

H351: 怀疑引起遗传缺陷 H302: 吞食有害

Statement of Preventive Measures：

P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P330: 漱口 P203: 使用前，获取、阅读并遵守所有安全说明。 P301+P317: 如果被吞咽：请寻求医疗帮助。 P318: 如果暴露或担心，请就医。