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CZC-54252

Dangerous Goods

CAS number：1191911-27-9    molecular formula：C22H25ClN6O4S

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Specs
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physicochemical properties
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overview

compound introduction

Information CZC-54252 CZC-54252 is a potent and selective LRRK2 inhibitor with IC50s of 1.28 nM and 1.85 nM for human wild type LRRK2 and G2019S LRRK2, respectively. Targets LRRK2 (WT) (Cell-free assay); LRRK2 (G2019S) (Cell-free assay) 1.28 nM; 1.85 nM

Specs

Chinese alias-
English aliasDTXSID501110376 | N-(2-((5-Chloro-2-((2-methoxy-4-morpholinophenyl)amino)pyrimidin-4-yl)amino)phenyl)methanesulfonamide | CHEBI:78414 | BDBM538130 | n-(2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)pyrimidin-4-ylamino)phenyl)methanesulfonamide | EX-A22
CAS number1191911-27-9molecular formulaC22H25ClN6O4S
molecular weight504.99 g/molExact mass10mM in DMSO
PSA126.000 Ųlogp3.300

numbering system

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physicochemical properties

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Safety information

Signal word：
Warning
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H302: 吞食有害
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。

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