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GSK3787

Dangerous Goods

CAS number:188591-46-0    molecular formula:C15H12ClF3N2O3S

overview

compound introduction

GSK3787是不可逆的PPARδ选择性拮抗剂,pIC50为6.6,对hPPARα和hPPARγ无亲和力。A potent and selective peroxisome proliferatior-activated recepter δ antagonist GSK3787 is as a selective and irreversible antagonist of PPARδ with pIC50 of 6.6, with no measurable affinity for hPPARα or hPPARγ. A potent and selective peroxisome proliferatior-activated recepter δ antagonist

Specs

Chinese alias-
English aliasGSK 3787 | SB19571 | J-012157 | 4-Chloranyl-N-(2-(5-(trifluoromethyl)pyridin-2-yl)sulfonylethyl)benzamide | 4-Chloro-N-[2-[[5-(trifluoromethyl)-2-pyridinyl]sulfonyl]ethyl]benzamide | GSK3787 | GSK-3787 | N1-(2-{[5-(trifluoromethyl)-2-pyridyl]sulfonyl}ethy
CAS number188591-46-0molecular formulaC15H12ClF3N2O3S
molecular weight392.78 g/molExact mass≥98%
PSA84.500 Ųlogp2.900

numbering system

No numbering system information yet

physicochemical properties

No physical and chemical property information yet

Safety information

pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H319: 引起严重眼睛刺激
Statement of Preventive Measures:
P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P337+P317: 如果眼睛刺激持续:寻求医疗帮助。
WGK Germany:
3

Production methods and uses

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Related

upstream information

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downstream information

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MSDS

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