compound introduction
Apremilast (CC-10004)是一种口服生物有效的PDE4和TNF-α抑制剂，IC50分别为74 nM和77 nM。 Apremilast (CC-10004) is a potent and orally active PDE4 and TNF-α inhibitor with IC50 of 74 nM and 77 nM, respectively.
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Apremilast
Dangerous GoodsCAS number：608141-41-9 molecular formula：C22H24N2O7S
overview
Specs
| Chinese alias | 阿普斯特 | ||
| English alias | CC-10004 | Apremilast [USAN] | Apremilast- Bio-X | HSDB 8221 | Propylenthioharnstoff [German] | APREMILAST [INN] | APREMILAST [VANDF] | FK-0727 | FT-0601433 | N-[2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-1,3-dioxoisoindol-4-yl]acetamide | ||
| CAS number | 608141-41-9 | molecular formula | C22H24N2O7S |
| molecular weight | 460.5 g/mol | Exact mass | - |
| PSA | 127.000 Ų | logp | 1.8 |
numbering system
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physicochemical properties
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Safety information
pictogram：
GHS08 , GHS07
Signal word：
Danger
Hazard Statement：
H302: 吞食有害 H312: 皮肤接触有害 H332: 吸入有害 H372: 通过长时间或反复暴露对器官造成损害 H360: 可能损害生育力或未出生的孩子 H361: 怀疑破坏生育力或未出生的孩子 H361fd: 怀疑破坏生育力；怀疑损害胎儿 H362: 可能对母乳喂养的孩子造成伤害
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P271: 仅在室外或通风良好的地方使用。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P304+P340: 如误吸入：将人转移到空气新鲜处
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MSDS
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