描述 胶原酶NB 8经过色谱纯化；因此，它具有很高的胶原蛋白水解活性。其他酶促活性，如梭菌蛋白酶，类胰蛋白酶活性和中性蛋白酶，以及内毒素水平都降低了。 应用 胶原酶NB 8适用于多种组织类型的解离。 规格 包含I类和II类胶原酶（1），以及水平降低的Clostripain，类胰蛋白酶活性和中性蛋白酶。 色谱纯化。 活性：≥0.90 U / mg 内毒素：≤100 EU / mg（Ph。Eur。） （Clostridiopeptidase A） EC 3.4.24.3 • Mr ca. 70 000 - 120 000 (collagenases) • CAS [9001-12-1] 参考和定义 单位定义： 胶原酶： 1 U在25°C（pH 7.1）下每分钟催化1 µmol 4-苯基偶氮苄氧基羰基-L-脯氨酰基-L-亮氨酰甘氨酰-L-脯氨酰基-D-精氨酸的水解。 内毒素： 欧洲药典 （1个内毒素单位等于WHO批准的参考标准内毒素（RSE）的1个国际单位）。 References 1. Bond, M.D. & van Wart, H.E. (1984) Biochemistry 23, 3077-3091 2. Wünsch, E. & Heidrich, H.G. (1963) Hoppe-Seyler's Z. Physiol. Chem. 333, 149-51. Collagenase NB 8 is chromatographically purified; therefore it contains a high collagenolytic activity. The additional enzymatic activities like clostripain, trypsin-like activity and neutral protease, as well as the endotoxin level are reduced. Application Collagenase NB 8 is suitable for dissociation of a broad variety of tissue types. Specifications Contains class I and class II collagenase (1) as well as reduced levels of clostripain, trypsin-like activities and neutral protease. Chromatographically purified. Activity (Wünsch): ≥ 0.90 U/mg Endotoxin: ≤ 100 EU/mg (Ph. Eur.) (Clostridiopeptidase A) EC 3.4.24.3 • Mr ca. 70 000 - 120 000 (collagenases) • CAS [9001-12-1] References and Definitions Unit definition: Collagenase: 1 U according to Wünsch (2) catalyzes the hydrolysis of 1 µmole 4-phenylazobenzyloxycarbonyl-L-prolyl-L-leucylglycyl-L-prolyl-D-arginine per minute at 25 °C, pH 7.1. Endotoxin: Ph. Eur. (1 Endotoxin Unit is equal to 1 International Unit of a WHO approved reference standard endotoxin (RSE)). References 1. Bond, M.D. & van Wart, H.E. (1984) Biochemistry 23, 3077-3091 2. Wünsch, E. & Heidrich, H.G. (1963) Hoppe-Seyler's Z. Physiol. Chem. 333, 149-51.
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胶原酶 NB 8 来源于溶组织梭菌
Dangerous GoodsCAS number：unknown molecular formula：
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | Collagenase I | Collagenase Type II | (5S,6S,9R,10S,13S,17S,23S,24S,27R,28S,31S,35S)-5,6,9,13,17,23,24,27,31,35-Decamethyl-10,28-dioctyl-2,20-diazanonacyclo[19.15.0.03,19.05,17.06,14.09,13.023,35.024,32.027,31]hexatriaconta-1(21),2,19-triene | ||
| CAS number | unknown | molecular formula | |
| molecular weight | - | Exact mass | - |
| PSA | - | logp | - |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram：
GHS08
Signal word：
Warning
Hazard Statement：
H334: 吸入可能引起过敏或哮喘病症状或呼吸困难
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P501: 将内容物/容器处理到。。。 P284: 如果通风不良，请佩戴呼吸防护装置。
WGK Germany：
1
Personal protective equipment：
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Production methods and uses
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MSDS
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