7-羟基香豆素葡萄糖醛酸钠盐是香豆素和7-羟基香豆素II期的标记代谢产物。7-羟基香豆素葡萄糖醛酸钠盐可用作分析7-羟基香豆素代谢的标准品。7-羟基香豆素葡糖醛酸钠盐是与单独的探针底物（如氯唑酮和7-羟基香豆素）孵育1小时后最终形成的代谢产物之一。在将HepaRG暴露于原始探针底物后，所形成的7-羟基香豆素葡糖醛酸钠盐的测定浓度可指示UGT酶的存在。在AR-CALUX中的LC-MS / MS分析测试中未检测到7-羟基香豆素葡萄糖醛酸钠盐。 7-Hydroxycoumarin glucuronide sodium salt is a labelled metabolite of Coumarin and 7-hydroxycoumarin phase II. 7-Hydroxycoumarin glucuronide sodium salt can be used as a standard for the analysis of 7-hydroxy coumarin metabolism. 7-Hydroxycoumarin glucuronide sodium salt was one of the eventually formed metabolites following a 1 hour incubation experiment with individual probe substrates, such as Chlorzoxazone and 7-hydroxycoumarin. The measured concentration of formed 7-Hydroxycoumarin glucuronide sodium salt can be indicative of the presence of UGT enzyme after exposure of HepaRG to the original probe substrate. 7-Hydroxycoumarin glucuronide sodium salt was undetectable in an LC-MS/MS analysis test in AR-CALUX. Application： 7-Hydroxycoumarin glucuronide sodium salt can be used as a standard for the analysis of 7-hydroxycoumarin metabolites；Phase II (UDP-GT) metabolite of 7-hydroxycoumarin；Useful as a pharmacokinetic standard in metabolic studies.
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7-Hydroxycoumarin glucuronide sodium salt
Dangerous GoodsCAS number：168286-98-4 molecular formula：C15H13NaO9
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | 7-Hydroxycoumarin glucuronide sodium salt | 7-Hydroxy coumarin glucuronide (sodium salt) | A-D-Glucuronide Sodium Salt | MFCD00674902 | 7-Hydroxy Coumarin beta-D-Glucuronide Sodium Salt | 7-Hydroxycoumarin glucuronide sodium salt is known as a 7-hydroxy c | ||
| CAS number | 168286-98-4 | molecular formula | C15H13NaO9 |
| molecular weight | 360.25 g/mol | Exact mass | ≥98% |
| PSA | 146.000 Ų | logp | - |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H302: 吞食有害 H312: 皮肤接触有害 H332: 吸入有害
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。 P362+P364: 脱掉沾污的衣服，清洗后方可重新使用
WGK Germany：
3
Personal protective equipment：
dust mask type N95 (US), Eyeshields, Gloves
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
No downstream information yet
MSDS
Found 1 shareMSDS
168286-98-4|7-hydroxycoumarin Β-d-glucuronide Sodium|7-hydroxycoumarin Β-d-glucuronide Sodium
