MBCQ是PDE5A的选择性抑制剂(cGMP特异性磷酸二酯酶,IC | 50 | = 19 nM)。 应用: MBCQ 是一种有效的选择性 cGMP 特异性磷酸二酯酶 (PDE V; PDE5) 抑制剂,IC50 为 19 nM。MBCQ 对其他 PDE 同工酶没有抑制活性,IC50 均大于 100 µM。MBCQ 通过特异性抑制 cGMP-PDE 来扩张冠状动脉。 MBCQ is a selective inhibitor of PDE5A (cGMP-specific phosphodiesterase, IC|50|=19 nM).
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MBCQ
Dangerous GoodsCAS number:150450-53-6 molecular formula:C16H12ClN3O2
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | NCGC00161596-01 | UPCMLD-DP008:002 | DTXSID60425013 | HMS1361J06 | CHEBI:93134 | AKOS005600215 | 4-((3,4-Methylenedioxybenzyl)amino)-6-chloroquinazoline | HMS1989J06 | BDBM50038991 | KBioGR_000184 | STL555823 | CNODHOSDWZLJGA-UHFFFAOYSA-N | N-(Benzo[d][1, | ||
| CAS number | 150450-53-6 | molecular formula | C16H12ClN3O2 |
| molecular weight | 313.74 g/mol | Exact mass | ≥98% |
| PSA | 56.300 Ų | logp | 3.800 |
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WGK Germany:
3
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