NDMC101 是一种有效的破骨细胞形成 (osteoclastogenesis) 抑制剂,通过下调 NFATc1 调控基因表达抑制破骨细胞分化。NDMC101 与 DPP4 底物相似,并且通过抑制 DPP4 而抑制早期 T 细胞激活的重要抑制剂。NDMC101 可用于骨疾病的研究,如类风湿关节炎、滑膜炎等。 Information NDMC101 is a potent inhibitor of osteoclastogenesis that inhibits osteoclast differentiation via down-regulation of NFATc1-modulated gene express. NDMC101 is also a significant inhibitor of early T-cell activation via DPP4 inhibition.NDMC101 is a potent osteoclastogenesis inhibitor and inhibits osteoclast differentiation via down-regulation of NFATc1-modulated gene expression. NDMC101 is similar to the DPP4 substrate and is a significant inhibitor of early T-cell activation via DPP4 inhibition. NDMC101can be used for study of bone disorders, such as rheumatoid arthritis, and synovial inflammation et al。
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NDMC101
Dangerous GoodsCAS number:1308631-40-4 molecular formula:C13H9ClFNO2
overview
compound introduction
Specs
| Chinese alias | N-(4-氯-2-氟苯基)-2-羟基苯甲酰胺 | ||
| English alias | HS-Cm | A900355 | NCGC00402296-03 | AS-16724 | AKOS009125225 | 1308631-40-4 | SCHEMBL12099327 | ndmc101 | NDMC101, >=98% (HPLC) | NUQWCDAXACRITO-UHFFFAOYSA-N | HY-124958 | NSC812943 | NSC-812943 | N-(4-chloro-2-fluorophenyl)-2-hydroxybenzamide | N-(4-chlo | ||
| CAS number | 1308631-40-4 | molecular formula | C13H9ClFNO2 |
| molecular weight | 265.67 g/mol | Exact mass | ≥98% |
| PSA | 49.300 Ų | logp | 4.000 |
numbering system
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physicochemical properties
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Safety information
pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染:用水充分清洗。 P321: 特殊处理(请参阅此标签上的...)。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P304+P340: 如误吸入:将人转移
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MSDS
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