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AR7

Dangerous Goods

CAS number:80306-38-3    molecular formula:C15H12ClNO

overview

compound introduction

Information AR7 AR7 is a retinoic acid receptor α (RARα) antagonist. application: AR7 has been used: • as chaperone-mediated autophagy (CMA) activator to study the activity of CMA in rat liver lysosomes • as a CMA activator to study its effects on expression of DEAD-box helicase 3 X-linked (DDX3X), eukaryotic translation initiation factor 4A1 (EIF4A1), and eukaryotic translation initiation factor 4H (EIF4H) in cancer cells • to study its effects on synuclein α (SNCA) oligomer levels in mature primary cortical neurons

Specs

Chinese alias7-氯-3-(4-甲基苯基)-2H-1,4-苯并恶嗪
English aliasMFCD27978377 | SCHEMBL12206685 | 7-chloro-3-(4-methylphenyl)-2H-1,4-benzoxazine | AKOS032946191 | EX-A1249 | BCP25687 | HY-101106 | AR7 | AR-7 | 7-Chloro-3-(p-tolyl)-2H-benzo[b][1,4]oxazine | 7-chloro-3-p-tolyl-2H-benzo[b][1,4]oxazine | NCGC00347937-01 |
CAS number80306-38-3molecular formulaC15H12ClNO
molecular weight257.71 g/molExact mass10mM in DMSO
PSA21.600 Ųlogp4.100

numbering system

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physicochemical properties

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Safety information

pictogram:
GHS09
Signal word:
Warning
Hazard Statement:
H410: 对水生生物有剧毒并具有长期持续影响
Statement of Preventive Measures:
P273: 避免释放到环境中。 P501: 将内容物/容器处理到。。。
WGK Germany:
3

Production methods and uses

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