CAS number：603139-19-1 molecular formula：C25H27F4N3O3S
Odanacatib (MK-0822)是一种有效的，选择性的，cathepsin K(人/兔)中性抑制剂，IC50为0.2 nM/1 nM，对脱靶的cathepsin B， L， S具有高度选择性。Phase 3 A cathepsin K inhibitor. Odanacatib (MK 0822) is a potent, selective, and neutral inhibitor of cathepsin K (human/rabbit) with IC50 of 0.2 nM/1 nM, and demonstrated high selectivity versus off-target cathepsin B, L, S. Phase 3.
| Chinese alias | - | ||
| English alias | NSC-82320 | Odanacatib | (2S)-N-(1-cyanocyclopropyl)-4-fluoro-4-methyl-2-[[(1S)-2,2,2-trifluoro-1-[4-(4-methylsulfonylphenyl)phenyl]ethyl]amino]pentanamide | AKOS000320210 | Odanacatib [USAN] | SMR004676504 | N1-(1-cyanocyclopropyl)-4-fluoro-N2-{(1S)-2,2, | ||
| CAS number | 603139-19-1 | molecular formula | C25H27F4N3O3S |
| molecular weight | 525.56 g/mol | Exact mass | - |
| PSA | 107.000 Ų | logp | 4.1 |
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