CAS number：170151-24-3 molecular formula：C14H15F2N3S·HCl
Nepicastat (SYN-117) HCl是一种有效的，选择性的牛和人类dopamine-β-hydroxylase（多巴胺-β-羟氨）抑制剂，IC50分别为8.5 nM和9 nM，对12种其他酶13种神经递质受体几乎没有亲和力。 Nepicastat (SYN-117) HCl is a potent and selective inhibitor of both bovine and human dopamine-β-hydroxylase with IC50 of 8.5 nM and 9 nM, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors. An inhibitor to bovine and human dopamine-beta-hydroxylase activity.
| Chinese alias | 内匹司他盐酸盐 | ||
| English alias | SCHEMBL3418494 | 5-(aminomethyl)-1-[(2S)-5,7-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl]-2,3-dihydro-1H-imidazole-2-thione hydrochloride | MFCD00954638 | Nepicastat HCl | Nepicastat hydrochloride anhydrous | C14H16ClF2N3S | NCGC00015263-02 | Nepicastat (S | ||
| CAS number | 170151-24-3 | molecular formula | C14H15F2N3S·HCl |
| molecular weight | 331.81 g/mol | Exact mass | ≥98% |
| PSA | 73.400 Ų | logp | - |
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