compound introduction
SZL P1-41 是一种特异的 Skp2 抑制剂，结合在 Skp2 的 F-box 域以防止与 Skp1 关联和 Skp2 SCF 复合物形成。与 Skp2 缺乏一样，SZL P1-41 增加 p27 介导的凋亡/衰老，同时损害 Akt 驱动的糖酵解。具有抗肿瘤活性。
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SZL P1-41
Dangerous GoodsCAS number：222716-34-9 molecular formula：C24H24N2O3S
overview
Specs
| Chinese alias | 3-(2-苯并噻唑基)-6-乙基-7-羟基-8-(1-哌啶基甲基)-4H-1-苯并吡喃-4-酮 | ||
| English alias | 3-(2-Benzothiazolyl)-6-ethyl-7-hydroxy-8-(1-piperidinylmethyl)-4H-1-benzopyran-4-one | ||
| CAS number | 222716-34-9 | molecular formula | C24H24N2O3S |
| molecular weight | 420.52 g/mol | Exact mass | ≥98%(HPLC) |
| PSA | 90.900 Ų | logp | 4.800 |
numbering system
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physicochemical properties
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Safety information
pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H302: 吞食有害
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。
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MSDS
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