AZD5904 是一种不可逆的人髓过氧化物酶选择性抑制剂,其IC50=140 nM,在小鼠和大鼠中也具有相似的效力。 AZD5904 is a potent and irreversible inhibitor of human Myeloperoxidase (MPO, IC50: 140 nM) which has similar potency in mouse and rat.
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AZD5904
Dangerous GoodsCAS number:618913-30-7 molecular formula:C10H12N4O2S
overview
compound introduction
Specs
| Chinese alias | AZD 5904 | AZD-5904 | ||
| English alias | 2-sulfanylidene-3-[(2R)-tetrahydro-2-furanylmethyl]-1,2,3,7-tetrahydro-6H-purin-6-one | AZD 5904 [WHO-DD] | 3-[[(2~{R})-oxolan-2-yl]methyl]-2-sulfanylidene-9~{H}-purin-6-one | 62A9CG81VN | Q27074766 | MS-23562 | 1,2,3,9-Tetrahydro-3-(((2R)-tetrahydro-2-fu | ||
| CAS number | 618913-30-7 | molecular formula | C10H12N4O2S |
| molecular weight | 252.29 g/mol | Exact mass | - |
| PSA | 102.000 Ų | logp | 0.500 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram:
GHS08
Signal word:
Warning
Hazard Statement:
H361: 怀疑破坏生育力或未出生的孩子
Statement of Preventive Measures:
P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P203: 使用前,获取、阅读并遵守所有安全说明。 P318: 如果暴露或担心,请就医。
Production methods and uses
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upstream information
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downstream information
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MSDS
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