Pimavanserin (ACP-103) 是一种高效选择性的5-HT2A反向激动剂,其pIC50 为8.73,用于治疗帕金森病相关的精神错乱。 Product Describtion: Pimavanserin is an effective and specific serotonin 5-HT2A inverse agonist (pIC50: 8.73), used in the therapy of psychosis associated with Parkinson's disease. Product Application: Pimavanserin tartrate is a 5-HT2A inverse agonist that reverses psychosis-like behaviours and has the potential to treat various other neuropsychiatric disorders such as schizophrenia and Parkinson’s disease
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Pimavanserin Tartrate
Dangerous GoodsCAS number:706782-28-7 molecular formula:C50H68F2N6O4·C4H6O6
overview
compound introduction
Specs
| Chinese alias | 匹莫范色林 L-酒石酸盐 | 匹莫范色林酒石酸盐 | 酒石酸匹莫范色林 | ||
| English alias | 1-(4-fluorobenzyl)-3-(4-isobutoxybenzyl)-1-(1-methylpiperidin-4-yl)urea, ((2R,3R)-2,3-dihydroxysuccinate) (2:1) | bis(4-{[(4-fluorophenyl)methyl]({[4-(2-methylpropoxy)phenyl]methyl}carbamoyl)amino}-1-methylpiperidin-1-ium) (2R,3R)-2,3-dihydroxybutanedioa | ||
| CAS number | 706782-28-7 | molecular formula | C50H68F2N6O4·C4H6O6 |
| molecular weight | 1005.21 g/mol | Exact mass | 10mM in DMSO |
| PSA | 205.000 Ų | logp | - |
numbering system
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physicochemical properties
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Safety information
pictogram:
GHS05 , GHS07
Signal word:
Danger
Hazard Statement:
H302: 吞食有害 H318: 造成严重的眼睛损伤 H317: 可能引起皮肤过敏反应 H332: 吸入有害 H302+H332: 吞咽或吸入有害。
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染:用水充分清洗。 P321: 特殊处理(请参阅此标签上的...)。 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P304+P340: 如误吸入:将人转移到空气新鲜处,保持呼吸舒适体位。 P272: 被污染的工作服不允许离开工作场所 P333+
Production methods and uses
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Related
upstream information
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downstream information
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MSDS
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