SB 200646

Dangerous Goods

CAS number：143797-63-1 molecular formula：C15H14N4O

overview

Specs

numbering system

physicochemical properties

Safety information

Production methods and uses

MSDS

overview

compound introduction

Information SB 200646 (SB 200646A) is a potent, selective and oral-active antagonist of5-HT2B/2Cover 5-HT2A receptor with 50 fold selectivity. The pKi for rat 5-HT2C receptor, rat 5-HT2B receptor and rat 5-HT2A receptor are 6.9, 7.5 and 5.2, respectively. SB 200646 has electrophysiological and anxiolytic properties in vivo. Targets 5-HT2B (rat) (Cell-free assay); 5-HT2C (Rat) (Cell-free assay); 5-HT2A (rat) (Cell-free assay) 7.5(pKi); 6.9(pKi); 5.2(pKi)

Specs

Chinese alias	-
English alias	HY-103129A \| 1-(1-methylindol-5-yl)-3-(3-pyridyl)urea \| UNII-RT8F72CL8L \| N-(1-Methyl-1H-indol-5-yl)-N'-3-pyridinylurea \| N-(1-METHYL-1H-INDOL-5-YL)-N-3-PYRIDINYLUREA \| Urea, N-(1-methyl-1H-indol-5-yl)-N'-3-pyridinyl- \| SCHEMBL173735 \| SB 200646A \| Q25323
CAS number	143797-63-1	molecular formula	C15H14N4O
molecular weight	266.3 g/mol	Exact mass	10mM in DMSO
PSA	59.000 Å²	logp	1.871

numbering system

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Safety information

pictogram：

GHS07

Signal word：

Warning

Hazard Statement：

H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H302: 吞食有害

Statement of Preventive Measures：

P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P301+P312: 如误吞咽：如感觉不适，呼叫急救中心/医生。