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(β,β-Dimethylacryl)shikonin

Dangerous Goods

CAS number:24502-79-2    molecular formula:C21H22O6

overview

compound introduction

(β,β-二甲基丙烯酰基)紫草素是从紫草中提取得到的一种萘醌衍生物,通过PI3K通路诱导 eNOS、VEGF 和 HIF-1α 的表达,促进血管生成,具有抗肿瘤活性。本品仅适用于科学研究。 β,β-Dimethylacrylshikonin (Isoarnebin I) is a naphthoquinone derivative isolated from Lithospermum erythrorhizon Sieb. et Zucc. , promotes angiogenesis by inducing eNOS, VEGF and HIF-1α expression through the PI3K-dependent pathway.β,β-Dimethylacrylshikonin has anti-tumor activity.This product is only suitable for scientific research.

Specs

Chinese aliasBATA,BATA-二甲基丙烯酰紫草素
English alias[(1R)-1-(5,8-dihydroxy-1,4-dioxonaphthalen-2-yl)-4-methylpent-3-enyl] 3-methylbut-2-enoate | 3-​methyl-​2-​butenoic acid (1R)​-​1-​(1,​4-​dihydro-​5,​8-​dihydroxy-​1,​4-​dioxo-​2-​naphthalenyl)​-​4-​methyl-​3-​penten-​1-​yl ester | Arnebin-1, Dimethylacry
CAS number24502-79-2molecular formulaC21H22O6
molecular weight370.40 g/molExact mass≥90%(HPLC)
PSA101.000 Ųlogp5.000

numbering system

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physicochemical properties

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Safety information

Signal word:
Warning
Hazard Statement:
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H302: 吞食有害
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染:用水充分清洗。 P301+P312: 如误吞咽:如感觉不适,呼叫急救中心/医生。

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