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Topotecan hydrochloride hydrate

Dangerous Goods

CAS number：123948-87-8(free base)    molecular formula：C23H23N3O5· xHCl · yH2O

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compound introduction

拓扑替康作为阳性对照，已被用作低氧条件下人神经胶质瘤细胞中HIF-1α 和VEGF抑制剂的鉴定和分析。它也被用于 体外 PA317细胞的凋亡检测。 Topotecan has been used as a positive control for the identification and analysis of HIF-1α and VEGF inhibitors in human glioma cells under hypoxic conditions. It has also been used for in vitro apoptosis assays in PA317 cells.

Specs

Chinese alias-
English alias-
CAS number123948-87-8(free base)molecular formulaC23H23N3O5· xHCl · yH2O
molecular weight421.45 (anhydrous frExact mass-
PSA-logp-

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Safety information

pictogram：
GHS08
Signal word：
Danger
Hazard Statement：
H340: 可能导致遗传缺陷 H361d: 怀疑损害胎儿
Statement of Preventive Measures：
P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P201: 使用前获取特殊说明 P308+P313: 如接触到或有疑虑：求医/就诊。 P202: 在阅读并理解所有安全预防措施之前，不要进行操作。

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