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KKII5

CAS number:6381-55-1    molecular formula:C16H14N2S

overview

compound introduction

KKII5 is a potent Lipoxygenase ( LOX-1 ) inhibitor with an IC 50 of 19 μM. KKII5 inhibits lipid peroxidation In Vitro KKII5 interacts with HIS499 of the cavity by forming one π–π stacking interaction between the phenyl ring of the molecule and the imidazole ring of HIS499. KKII5 (100 μM) strongly inhibits lipid peroxidation with 98% inhibition. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:IC50: 19 μM (LOX-1)

Specs

Chinese alias-
English alias-
CAS number6381-55-1molecular formulaC16H14N2S
molecular weight266.36 g/molExact mass≥98%
PSA56.200 Ųlogp3.300

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