KKII5 is a potent Lipoxygenase ( LOX-1 ) inhibitor with an IC 50 of 19 μM. KKII5 inhibits lipid peroxidation In Vitro KKII5 interacts with HIS499 of the cavity by forming one π–π stacking interaction between the phenyl ring of the molecule and the imidazole ring of HIS499. KKII5 (100 μM) strongly inhibits lipid peroxidation with 98% inhibition. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:IC50: 19 μM (LOX-1)
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KKII5
CAS number:6381-55-1 molecular formula:C16H14N2S
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 6381-55-1 | molecular formula | C16H14N2S |
| molecular weight | 266.36 g/mol | Exact mass | ≥98% |
| PSA | 56.200 Ų | logp | 3.300 |
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