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Ganglioside GD1a disodium salt

CAS number:12707-58-3    molecular formula:C84H148N4O39•x(Na)

overview

compound introduction

神经节苷脂GD1a二钠盐是哺乳动物大脑中的主要神经节苷脂。被认为是干细胞生长的分化标记。已对| S表现出对吞噬作用和吞噬-溶酶体(PL)融合的刺激作用。金黄色|。显示出可调节CaP依赖的GAP-43的翻译后调控。显示可诱导GAP-43快速磷酸化并刺激CAP-43的ca依赖性蛋白水解。神经节苷脂GD1a二钠盐是PKC的抑制剂。 Ganglioside GD1a disodium salt is the major ganglioside in the mammalian brain. Believed to be a differentiation marker for stem cell growth. Has shown a stimulatory effect on phagocytosis and phagosome-lysosome (P-L) fusion in a dose-dependent manner on|S. aureus|. Shown to modulate the Ca-dependent post-translational regulation of GAP-43. Shown to induce rapid phosphorylation of GAP-43 and stimulate ca-dependent proteolysis of GAP-43. Ganglioside GD1a disodium salt is an inhibitor of PKC.

Specs

Chinese alias-
English aliasDisialoganglioside GD1a*2Na | ganglioside GDla | C84H146N4O39.2Na | Ganglioside GD1a disodium salt | Ganglioside GD1 | Ganglioside GD1a (VAN) | CWLDKTAXQZEVQN-CUEXFKMESA-L | Ganglioside, GD1a | GD(1a) Ganglioside | GD1a ganglioside | Disialoganglioside GD
CAS number12707-58-3molecular formulaC84H148N4O39•x(Na)
molecular weight1838.082299 g/molExact mass≥98%
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