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Dxd

Dangerous Goods

CAS number：1599440-33-1    molecular formula：C26H24FN3O6

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numbering system
physicochemical properties
Safety information
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overview

compound introduction

Dxd是一种有效的DNAtopoisomeraseI抑制剂，IC50值为0.31μM，可用作靶作用于HER2的抗体偶联药物ADC(DS-8201a)的有效载荷。 Product description： Dxd is a potent DNA topoisomerase I inhibitor, with an IC50 of 0.31 μM, used as a conjugated drug of HER2-targeting ADC (DS-8201a).

Specs

Chinese alias-
English aliasA936339 | N-[(10S,23S)-10-ethyl-18-fluoro-10-hydroxy-19-methyl-5,9-dioxo-8-oxa-4,15-diazahexacyclo[14.7.1.0,.0,.0,.0,tetracosa-1,6(11),12,14,16,18,20(24)-heptaen-23-yl]-2-hydroxyacetamide | AC-32494 | AT21797 | EX-A4319 | SCHEMBL16485136 | UNII-OQM5SD32BQ
CAS number1599440-33-1molecular formulaC26H24FN3O6
molecular weight493.48 g/molExact mass≥98%
PSA129.000 Ųlogp0.000

numbering system

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physicochemical properties

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Safety information

pictogram：
GHS06
Signal word：
Danger
Hazard Statement：
H301: 吞咽会中毒
Statement of Preventive Measures：
P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P301+P310+P330: 如果吞咽：漱口。立即致电中毒中心/医生。

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