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GNF-2

Dangerous Goods

CAS number：778270-11-4    molecular formula：C18H13F3N4O2

overview
Specs
numbering system
physicochemical properties
Safety information
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overview

compound introduction

GNF-2是一种高选择性，非ATP竞争性的Bcr-Abl抑制剂，对Flt3-ITD， Tel-PDGFR， TPR-MET和Tel-JAK1转化的肿瘤细胞没有作用活性。 GNF-2 is a highly selective non-ATP competitive inhibitor of Bcr-Abl, shows no activity to Flt3-ITD, Tel-PDGFR, TPR-MET and Tel-JAK1 transformed tumor cells. An inhibitor of c-Abl and Bcr-abl activity

Specs

Chinese alias-
English aliasGNF-2 | 778270-11-4 | 3-(6-((4-(Trifluoromethoxy)phenyl)amino)pyrimidin-4-yl)benzamide | GNF 2 | GNF2 | 3-[6-[4-(trifluoromethoxy)anilino]pyrimidin-4-yl]benzamide | 6D7Q9Z2W7T | CHEMBL483847 | 3-(6-{[4-(Trifluoromethoxy)phenyl]amino}pyrimidin-4-Yl)benzami
CAS number778270-11-4molecular formulaC18H13F3N4O2
molecular weight374.32 g/molExact mass-
PSA90.100 Ųlogp3.800

numbering system

No numbering system information yet

physicochemical properties

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Safety information

pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P304+P340: 如误吸入：将人转移
WGK Germany：
3
Personal protective equipment：
dust mask type N95 (US), Eyeshields, Gloves

Production methods and uses

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MSDS

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