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PBTZ169

Dangerous Goods

CAS number：1377239-83-2    molecular formula：C20H23F3N4O3S

overview
Specs
numbering system
physicochemical properties
Safety information
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overview

compound introduction

PBTZ169 是具有杀菌作用的苯并噻嗪酮，也有抗结核作用。它也是一种DprE1有效抑制剂，可通过与活性位点 Cys387 残基形成共价键来抑制必需的黄素蛋白 DprE1。 PBTZ169 (macozinone)是DprE1的不可逆性抑制剂。 应用： Macozinone (PBTZ169) 是一种杀菌型苯并噻嗪酮，也是有效的 DprE1 抑制剂。Macozinone 可通过与活性位点 Cys387 残基形成共价键来抑制必需的黄素蛋白 DprE1。Macozinone 有抗结核作用。 Information PBTZ169 PBTZ169 (macozinone), an antibiotic with antimycobacterial activity, is an irreversible inhibitor of DprE1 .

Specs

Chinese alias-
English aliasMACOZINONE [WHO-DD] | HY-12903 | InChI=1/C8H8Br2/c9-5-7-2-1-3-8(4-7)6-10/h1-4H,5-6H | BS-15317 | Macozinone | 2-[4-(cyclohexylmethyl)piperazin-1-yl]-8-nitro-6-(trifluoromethyl)-1,3-benzothiazin-4-one | BDBM50515570 | PBTZ-169;PBTZ 169;Macozinone | YH65042
CAS number1377239-83-2molecular formulaC20H23F3N4O3S
molecular weight456.48 g/molExact mass≥98%
PSA107.000 Ųlogp4.7

numbering system

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physicochemical properties

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Safety information

pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H302: 吞食有害
Statement of Preventive Measures：
P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P330: 漱口 P301+P317: 如果被吞咽：请寻求医疗帮助。

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