Tedizolid Phosphate

Dangerous Goods

CAS number：856867-55-5 molecular formula：C17H16FN6O6P

overview

Specs

numbering system

physicochemical properties

Safety information

Production methods and uses

MSDS

overview

compound introduction

Tedizolid phosphate (TR-701FA) 是 MAO-A 和 MAO-B 抑制剂，具有抗革兰氏阳性菌的活性。 Information Tedizolid (TR-701FA) is an oxazolidinone-class antibiotic. Tedizolid phosphate is a phosphate ester prodrug of the active compound tedizolid. In vitro Tedizolid (TR-700, formerly torezolid) is the active moiety of the prodrug tedizolid phosphate (TR-701), a next-generation oxazolidinone, with high potency against Gram-positive species, including methicillin-resistant Staphylococcus aureus (MRSA). Tedizolid is 4-fold more potent than linezolid against PRSP isolates in vitro. In vivo Tedizolid has excellent penetration into pulmonary epithelial lining fluid (ELF). Tedizolid phosphate administered to mice orally or intravenously is effective in vivo against systemic infection with PRSP isolates. Oral tedizolid phosphate is also effective in vivo against pneumonia induced with a PSSP strain. Product Describtion: Tedizolid phosphate (TR-701FA) is a novel oxazolidinone with activity against Gram-positive pathogens.

Specs

Chinese alias	(R)-(3-(3-氟-4-(6-(2-甲基-2H-四唑-5-基)吡啶-3-基)苯基)-2-氧代恶唑烷-5-基)甲基二氢磷酸酯
English alias	[(5R)-3-{3-Fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl]phenyl}-2-oxooxazolidin-5-yl]methyl hydrogen phosphate \| Tedizolid phosphate [USAN] \| A863474 \| MFCD28098176 \| TEDIZOLID PHOSPHATE [JAN] \| (5R)-3-[3-Fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-p
CAS number	856867-55-5	molecular formula	C17H16FN6O6P
molecular weight	450.32 g/mol	Exact mass	≥98%
PSA	153.000 Å²	logp	1.712

numbering system

No numbering system information yet

physicochemical properties

No physical and chemical property information yet

Safety information

pictogram：

GHS08 , GHS09

Signal word：

Warning

Hazard Statement：

H373: 通过长时间或反复暴露对器官造成损害 H400: 对水生生物有剧毒 H410: 对水生生物有剧毒并具有长期持续影响 H361: 怀疑破坏生育力或未出生的孩子

Statement of Preventive Measures：

P273: 避免释放到环境中。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P391: 收集溢出物 P203: 使用前，获取、阅读并遵守所有安全说明。 P318: 如果暴露或担心，请就医。 P319: 如果你感到不适，请寻求医疗帮助。