β-雌二醇 3-硫酸钠盐是一种甾体激素，具有雌激素活性。它通过与细胞核内的雌激素受体（雌激素受体α和β）结合发挥作用。这种结合会引发一连串的分子事件，导致基因表达的调节和各种细胞过程的调控。β-雌二醇 3-硫酸钠盐的作用机制包括影响目标基因的转录，从而影响细胞的生理反应。通过与雌激素受体相互作用，β-雌二醇 3-硫酸钠盐在调节细胞增殖、分化和凋亡方面发挥作用。它在分子水平上的活性有助于调节各种信号传导途径和细胞功能，使其成为研究激素信号传导和相关生物过程的一个重要组成部分。 β-Estradiol 3-sulfate sodium salt functions as a steroid hormone and exhibits estrogenic activity. It acts by binding to estrogen receptors, estrogen receptor alpha and beta, within the cell nucleus. This binding initiates a cascade of molecular events, leading to the regulation of gene expression and the modulation of various cellular processes. β-Estradiol 3-sulfate sodium salt′s mechanism of action involves influencing the transcription of target genes, thereby impacting the physiological responses of the cells. By interacting with estrogen receptors, β-Estradiol 3-sulfate sodium salt plays a role in the regulation of cell proliferation, differentiation, and apoptosis. Its activity at the molecular level contributes to the modulation of various signaling pathways and cellular functions, making it a relevant component in studies exploring hormone signaling and related biological processes.
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17β-Estradiol 3-O-Sulfate (sodium salt)
Dangerous GoodsCAS number：4999-79-5 molecular formula：C18H23O5S • Na
overview
compound introduction
Specs
| Chinese alias | 雌二醇-3-硫酸盐 | BETA-雌二醇 3-硫酸钠盐 | β-雌二醇 3-硫酸钠盐 | ||
| English alias | Estradiol-3-sulfate | Estradiol-17beta 3-sulfate | Estradiol 3-sulphate | 17beta-estradiol 3-sulfate | CHEBI:4866 | 4NKQ3751P6 | [(8R,9S,13S,14S,17S)-17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] hydrogen sulfate | | ||
| CAS number | 4999-79-5 | molecular formula | C18H23O5S • Na |
| molecular weight | 374.43 g/mol | Exact mass | ≥98% |
| PSA | 92.200 Ų | logp | 2.100 |
numbering system
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physicochemical properties
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Safety information
pictogram：
GHS08 , GHS07
Signal word：
Danger
Hazard Statement：
H351: 怀疑引起遗传缺陷 H302: 吞食有害 H312: 皮肤接触有害 H332: 吸入有害 H360: 可能损害生育力或未出生的孩子
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。 P362+P364: 脱掉沾污的衣
Production methods and uses
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Related
upstream information
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downstream information
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MSDS
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