SKI II是一种合成的鞘氨醇激酶 (SK) 抑制剂, 抑制SK1和SK2, IC50值分别为78 μM和45 μM。 SKI-II is a synthetic inhibitor of sphingosine kinase (SK) activity with IC50 of 78 μM for SK1 and 45 μM for SK2. Human cisplatin-resistant gastric cancer cell line was treated with SKI-II to study the mechanism of reversion of multidrug resistance.
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SKI II
Dangerous GoodsCAS number:312636-16-1 molecular formula:C15H11ClN2OS
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | CCG-265019 | HMS3413G03 | SKI II | Ski ii (sphk-i2) | HMS3650M12 | NCGC00092309-01 | SKI 2 | BDBM50312869 | HMS3677G03 | SR-01000946305 | A820778 | 3vzd | CHEBI:92375 | HMS3653G15 | HMS3674I15 | STL255710 | HMS3268L05 | FT-0644394 | NCGC00092309-02 | 4-[[ | ||
| CAS number | 312636-16-1 | molecular formula | C15H11ClN2OS |
| molecular weight | 302.78 g/mol | Exact mass | - |
| PSA | 73.400 Ų | logp | 4.800 |
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Safety information
WGK Germany:
3
Personal protective equipment:
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
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