CAS number：209984-57-6 molecular formula：C26H23F2N3O4
LY411575是γ-secretase抑制剂，基于膜和细胞的实验IC50分别为0.078 nM/0.082 nM，还能抑制Notch clevage，IC50为0.39 nM。A potent γ-secretase inhibitor LY411575 is a potent γ-secretase inhibitor with IC50 of 0.078 nM/0.082 nM (membrane/cell-based), also inhibits Notch cleavage with IC50 of 0.39 nM in APP or NΔE expressing HEK293 cells. A potent γ-secretase inhibitor
| Chinese alias | - | ||
| English alias | AC-32717 | LY 411,575 | N(2)-[(2S)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]-N-[(7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-L-alaninamide | HMS3884D16 | LY-411575, >=97% (HPLC) | M&B 17,803A | HY-50752 | MFCD09832551 | (2S)-2-[[(2S)-2-(3,5-d | ||
| CAS number | 209984-57-6 | molecular formula | C26H23F2N3O4 |
| molecular weight | 479.48 g/mol | Exact mass | ≥98% |
| PSA | 98.700 Ų | logp | 3.000 |
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