PD184352 (CI-1040)是一种ATP非竞争性的MEK1/2抑制剂,IC50为17 nM,对MEK1/2的选择性比MEK5高100倍。 PD184352 (CI-1040) is an ATP non-competitive MEK1/2 inhibitor with IC50 of 17 nM, 100-fold more selective for MEK1/2 than MEK5 A MEK inhibitor.
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PD184352 (CI-1040)
Dangerous GoodsCAS number:212631-79-3 molecular formula:C17H14ClF2IN2O2
overview
compound introduction
Specs
| Chinese alias | 2-(2-氯-4-碘苯氨基)-N-(环丙基甲氧基)-3,4-二氟苯酰胺 | ||
| English alias | HMS3244G05 | P2174 | PD 184352CI-1040 | FT-0673543 | MFCD02683961 | 2-(2-Chloro-4-iodo-phenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide, CI-1040 | AC-25483 | CI-1040,PD184352 | DB12429 | GFMMXOIFOQCCGU-UHFFFAOYSA-N | PD184352, >=98% (HPLC) | US8575 | ||
| CAS number | 212631-79-3 | molecular formula | C17H14ClF2IN2O2 |
| molecular weight | 478.66 g/mol | Exact mass | - |
| PSA | 50.400 Ų | logp | 5.6 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram:
GHS09
Signal word:
Warning
Hazard Statement:
H400: 对水生生物有剧毒
Statement of Preventive Measures:
P273: 避免释放到环境中。 P501: 将内容物/容器处理到。。。 P391: 收集溢出物
WGK Germany:
3
Production methods and uses
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Related
upstream information
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downstream information
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MSDS
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