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Aurora A Inhibitor I

Dangerous Goods

CAS number:1158838-45-9    molecular formula:C31H31ClFN7O2

overview

compound introduction

Aurora A Inhibitor I是一种新型有效的,选择性Aurora A抑制剂,无细胞试验中IC50为3.4 nM,作用于Aurora A比作用于Aurora B选择性高1000倍。 Aurora A Inhibitor I is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay. It is 1000-fold more selective for Aurora A than Aurora B.

Specs

Chinese alias-
English aliasCHEBI:91365 | NCGC00346525-01 | NCGC00346525-10 | Aurora Inhibitor, 35 | BDBM31837 | Q27076171 | N-(2-Chlorophenyl)-4-[(2-{4-[2-(4-ethylpiperazin-1-yl)-2-oxoethyl]anilino}-5-fluoropyrimidin-4-yl)amino]benzamide | HMS3265L22 | Aurora A Inhibitor I | E98883
CAS number1158838-45-9molecular formulaC31H31ClFN7O2
molecular weight588.07 g/molExact mass-
PSA102.000 Ųlogp5.100

numbering system

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physicochemical properties

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Safety information

pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H302: 吞食有害
Statement of Preventive Measures:
P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P330: 漱口 P301+P317: 如果被吞咽:请寻求医疗帮助。
WGK Germany:
3

Production methods and uses

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MSDS

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